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L-Ergothioneine Powder Mushroom Extract 99%

Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.

EGT is accumulated into different cellular compartments via its specific transporter OCTN-1,abundantly expressed in mitochondrial DNA is especially vulnerable to stress because unlike nuclear DNA,there are no histones to protect mitochondrial DNA.Reactive oxygen species,like superoxides O2- generated in the mitochondria by respiration,are directly scavenged by EGT.EGT presents in the cytoplasm also scavenges a variety of ROS and reactive nitrogen species.EGT absorbs UV radiation and prevents DNA breaks and mutations.

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Detail

Function of Ergothioneine - THE LONGEVITY NUTRIENT

It's an amino acid, an important component in maintaining cellular health, which is able to cross cell membranes directly

1.Regulate neuronal activity

GABAB receptors are widely distributed in neurons and glial cells and play an important role in regulating neurotransmitter release and neuronal excitability.

2.Improve stress and enhance sleep quality

Increases the inhibitory effect of neurotransmission by increasing the activity of GABA receptors, thus helping to relieve stress and improve mood states. It reduces the activity of excitatory neurons in the brain, which promotes deeper, more restful sleep.

3.Repair skin barrier

GABA stimulates fibroblasts to synthesize collagen and hyaluronic acid, antioxidant, and promotes the repair of the skin barrier

Ergothionine's Application Scope:

1.Pharmaceutical field:

It's used internally for the treatment of cancer, cardiovascular and cerebrovascular diseases, central nervous system diseases, etc.; externally for the treatment of dermatologic and inflammatory diseases.

2.Food and Healthcare field:

Protect brain health, effectively promote the body's metabolism and immune function, to achieve the effect of delaying aging, improve sleep.

3.Cosmetic field:

Stimulate the antioxidant defense system of cells, hinder pigment formation and deposition, play a role in skin to improve dullness and minimize the appearance of fine lines.

Test Report:

Test Index	Standard Provision	Result
Appearance	White or Similar White Crystalline Powder	White Powder
Smell	Odorless	Odorless
Assay(Converted on Dry Basis)	>99%	99.7%
Purity(by HPLC)	>99%	99.96%
optical rotation	-30°~ -34°	-32.1°
Heavy Metal	<10ppm	<10ppm
Fe	<5ppm	Not Detected
Pb	<0.1mg/kg	Not Detected
Hg	<0.3mg/kg	Not Detected
As	<0.3mg/kg	Not Detected
Cr	<0.3mg/kg	0.088
Transmittance	≥99%	99.5%
PH	1.8-2.3	2.13
Water Content	≤1.0%	0.25%
Ash	≤1.0%	0.46%
Ethanol residue	<0.5%	0.15%
Loss on drying	≤0.5%	0.32%
Total plate count	<100CFU/g	<10CFU/g
Yeast and Molds	<10CFU/g	<10CFU/g
Number of Coliforms	Not Detectable	Not Detected
Staphylococcus Aureus	Not Detectable	Not Detected
Salmonella Count	Not Detectable	Not Detected
Listeria Monocytogenes	Not Detectable	Not Detected
Cronobacter sakazakii	Not Detectable	Not Detected
Bacillus Cereus	<50CFU/g	<10CFU/g
Dibutyl Phthalate	Not Detectable	Not Detected
Conclusion:The products Conforms to in-house